The old Du Froyo space in Dupont looks to be filled soon by a pet store called The Cheeky Puppy. Du Froyo opened in 2009 and closed less than one year later, in 2010.
The address is 1709 Connecticut Ave NW. This storefront is in a prime Dupont location, being one block from the Dupont Metro station and feet away from 42 bus line stops. It's also walkable from several in-town neighborhoods such as Embassy Row, Adams Morgan, U St, and Kalorama.
The Cheeky Puppy describes it self as serving "the unique needs of city-dwelling pet lovers." There's no opening date posted just yet, but my best guess is late 1Q or early 2Q of this year. Good luck Cheeky Puppy!